1861 John Deacon listed as licensee, previously 1859 a John Deacon of Fleet St listed as manufacturer.
In 1870, the Cambridge Arms was run as a beerhouse, the licence being transferred from Thomas Denman to John Knight, but Knight soon found himself in financial difficulties culminating in him leaving the Cambridge Arms the following March. He was eventually declared bankrupt to the tune of £196.11/6 in October of that year.
Rendell Voce took over from Knight, but he too only stayed for just over a year. This was not before he had an altercation with James Brown, who having just been released from prison, smashed the Cambridge Arms window, when refused a drink whilst drunk. James Brown then tried to commit suicide in his cell with his braces, on being discovered after he was heard making a gurgling noise he was cut down and handcuffed with hands behind his back, Brown was given 21 days for the offence at the Cambridge Arms and to be closely supervised whilst in Goal.

Then in October 1872 Mary Wightman took on the licence. Mary married Joseph Robert, so he then became licensee. Joseph Robert to James Tidd 1873.
Thomas Clarke, ran the pub with his wife Mary. Mary was once charged with unlawfully taking water belonging to the Leicester Waterworks Co in 1878. Thomas was to die here in 1880.
1889 The Cambridge Arms advertised for a Strong Girl aged 16, preferably from the Countryside.
In 1890, it was listed as brewing, Stephen Atkins the victualler. 1896 John Ward,
On the 10th of February 1900, the brewing equipment was auctioned off. Henry Flower landlord in April of that year.
J H Taylor Malster of Leicester recorded as the owner, Marston Thompson & Evershed-Brewery listed c 1900.
James Samson 1904-12 licensee when the pub was refused renewal, compensation paid £671.18 to the owner and £150 to the tenant, it does have J H Taylor as owner at the time-possible that Marstons were leaseholders, but it does not specify. The Cambridge Arms closed June 24th 1912.

Fleet St now off Lee Circle, Cambridge Arms no 52 on corner above letter T on Fleet Street